Just had the same idea, was a at a garden center today and they were selling what I presume were spores and my mind switched to hydroponics. I will do a bit of research myself and see what we can come up with.
As for Truffels, they are dependant on the roots of certain trees (Oaks are a common one), they would need to be massively genetically modified in order to grow them in "captivity", then I doubt they would have the same aroma and taste. Don't worry plenty of scientists are trying and I believe last year the genome was sequenced, the holy grail of mycology.
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