Yes Lettuce and Tomatoes and Greens and Herbs all grown not in a two-liter bottles but in a 16 ounce cups sitting in a cut off two liter bottle. Hydroponic plants don't need a lot of roots when you are delivering all the
nutrients to the plant. Hydroponically grown plants don't need a lot of roots unlike with dirt growing where the roots have to go looking for water and food. You want all the energy for producing fruit and not for root production. Unless you are growing potatoes or carets.